God of War et Shadow of The Colossus dominent les awards 2006 en raflant respectivement 6 nominations et 4 nominations.

Best Game
Animal Crossing: Wild World (Nintendo EAD/Nintendo)
- Katsuya Eguchi, Hisashi Nogami, Takashi Tezuka, Kazumi Totaka
God of War (Sony Computer Entertainment America)
- David Jaffe, Shannon Studstill
Guitar Hero (Harmonix Music Systems/RedOctane)
- Rob Kay, Greg LoPiccolo, Alex Rigopulos
Shadow of the Colossus (Sony Computer Entertainment Inc.)
- Kenji Kaido, Yasuhide Kobayashi, Fumito Ueda
The Movies (Lionhead Studios/Activision)
- Gary Carr, Peter Molyneux, Mark Webley

Best Audio
Call of Duty 2 (Infinity Ward/Activision)
- Mark Ganus
Electroplankton (Nintendo)
- Toshio Iwai, Koichi Kyuma, Yuichi Ozaki
God of War (Sony Computer Entertainment America)
- Dave Murrant
Guitar Hero (Harmonix Music Systems/RedOctane)
- Eric Brosius, Kasson Crooker
Project Gotham Racing 3 (Bizarre Creations/Microsoft Game Studios)
- Nick Bygrave, Guy Whitmore, Nick Wiswell

Character Design
City of Villains (Cryptic Studios/NCsoft Corporation)
- Ocala Bellows Kulig, Ryan Butts, Jay Doherty, Jeremy Mattson
God of War (Sony Computer Entertainment America)
- David Jaffe, Terry Smith, Charlie Wen
Oddworld: Stranger's Wrath (Oddworld Inhabitants/Electronic Arts)
- Lorne Lanning, Rich McKain, Iain Morton, Raymond Swanland
Psychonauts (Double Fine Productions/Majesco Entertainment Company)
- Scott Campbell
Shadow of the Colossus (Sony Computer Entertainment Inc.)
- Atsuko Fukuyama, Hitoshi Niwa, Shunpei Suzuki, Fumito Ueda

Game Design
Animal Crossing: Wild World (Nintendo EAD/Nintendo)
- Katsuya Eguchi, Hisashi Nogami, Takashi Tezuka, Kazumi Totaka
God of War (Sony Computer Entertainment America)
- David Jaffe
Nintendogs (Nintendo EAD/Nintendo)
- Tsutomu Kaneshige, Hideki Konno, Shigeru Miyamoto, Kiyoshi Mizuki
Psychonauts (Double Fine Productions/Majesco Entertainment Company)
- Erik Robson, Tim Schafer
Shadow of the Colossus (Sony Computer Entertainment Inc.)
- Junichi Hosono, Fumito Ueda

Best Technology
Battlefield 2: Modern Combat (Digital Illusions/Electronic Arts)
- Fred Gill, Måns Vestin
Guitar Hero (Harmonix Music Systems/RedOctane)
- Eran Egozy, Eric Malafeew, Phil Winston
Nintendogs (Nintendo EAD/Nintendo)
- Tsutomu Kaneshige
Project Gotham Racing 3 (Bizarre Creations/Microsoft Game Studios)
- Edmund Clay, Roger Perkins, Phil Teschner, Ian Wilson
Shadow of the Colossus (Sony Computer Entertainment Inc.)
- Jinji Horagai, Takuya Seki, Hajime Sugiyama, Masanobu Tanaka

Best Visual Arts
God of War (Sony Computer Entertainment America)
- Steve Caterson, Terry Smith, Charlie Wen
Project Gotham Racing 3 (Bizarre Creations/Microsoft Game Studios)
- Gren Atherton, Julie McGurren, Peter Roe, Kiki Wolfkill
Resident Evil 4 (Capcom Production Studio 4/Capcom Entertainment)
- Yusuke Hashimoto, Yoshiaki Hirabayashi, Yusuke Kan, Masaki Yamanaka
Shadow of the Colossus (Sony Computer Entertainment Inc.)
- Koji Hasegawa, Hironobu Nakano, Masanori Kajita, Fumito Ueda
We Love Katamari (Namco Limited/Namco Hometek)
- Keita Takahashi, Takeshi Ugajin

Best Writing
Freedom Force vs. The 3rd Reich (Irrational Games/Vivendi Universal Games)
- Ken Levine
God of War (Sony Computer Entertainment America)
- David Jaffe, Marianne Krawcyzk, Alex Stein
Indigo Prophecy (Quantic Dream/Atari)
- David Cage
Jade Empire (BioWare Corp./Microsoft Game Studios)
- Drew Karpyshyn, Brian Kindregan, Luke Kristjanson, Mike Laidlaw, Peter Thomas, Mac Walters
Psychonauts (Double Fine Productions/Majesco Entertainment Company)
- Tim Schafer, Erik Wolpaw

Best New Studio
ArenaNet (Guild Wars)
- Mike O'Brien, Jeff Strain, Patrick Wyatt
Double Fine Productions (Psychonauts)
- Caroline Esmurdoc, Tim Schafer
New Crayon Games (Bonnie's Bookstore)
- Phil Steinmeyer
TellTale Games (Bone: Out From Boneville)
- David Bogan, Kevin Bruner, Dan Connors, Troy Molander
Wideload Games (Stubbs the Zombie in Rebel Without a Pulse)
- Alexander Seropian

Innovation Award
Nintendogs (Nintendo EAD/Nintendo)
- Tsutomu Kaneshige
Guitar Hero (Harmonix Music Systems/RedOctane)
- Eric Brosius, Kasson Crooker