1 Nintendogs 840,000 (4,102,000)
2 New Super Mario Bros 485,000 (2,258,000)
3 Yoshi Island 2 462,500 (620,500)
4 Brain Age 369,500 (1,270,000)
5 Mario Kart DS 287,000 (1,729,500)
6 Pokemon Ranger 280,500 (514,000)
7 Pokemon Mysterious Dungeon: Blue Rescue Team 271,500 (865,500)
8 Hannah Montana 267,500 (339,000)
9 Kirby Squeak Squad 240,500 (240,500)
10 Big Brain Academy 217,500 (784,500)
11 Mario Hoops 3 on 3 213,500 (485,500)
12 Mario vs Donkey Kong 2: March of the Minis 210,000 (434,000)
13 Final Fantasy III 208,500 (376,500)
14 The Sims 2: Pets 194,500 (267,000)
15 Animal Crossing: Wild World 181,000 (1,156,500)
16 Castlevania: Portrait of Ruin DS 168,500 (168,500)
17 Happy Feet161,500 (161,500)
18 Cars 145,500 (372,000)
19 Super Mario 64 DS 137,500 (1,945,500)
20 Lego Star Wars II: The Original Trilogy 112,000 (250,500)